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    HbA1c variability linked to depression in elderly

    Variability in glycemic control as measured by HbA1c was associated with more depressive symptoms among elderly patients with type 2 diabetes, according to the results of a study published in Diabetes Care.

    “The results of the study demonstrate that variability in HbA1c over time (mean 8.7 years) is associated with the subsequent number of depressive symptoms in elderly subjects with type 2 diabetes,” researcher Ramit Ravona-Springer, MD, head of the Memory and Geriatric Psychiatry Clinic at the Sheba Medical Center in Tel Hashomer, Israel, told Medical Economics. “Surprisingly, mean HbA1c levels were not associated with subsequent number of depressive symptoms, suggesting that not all measures of glycemic control over time are effective in prediction of depressive symptoms.

    According to Ravona-Springer, depression and diabetes are both highly prevalent in the elderly and the risk for depression is doubled in the presence of diabetes.

    “Treatment guidelines for depression or its prevention are lacking in the context of diabetes in the older and growing segment of the population,” she said. “Since better glycemic control is associated with decreased risk for some diabetes- related complications, we aimed to analyze the relationship of glycemic control and depressive symptoms in a cohort of elderly patients with type 2 diabetes.”

    Next: Study details

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