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Laird Harrison
Aldehyde dehydrogenase implicated in mucous membrane pemphigoid
Preliminary studies suggest disulfiram could aid in the treatment of mucous membrane pemphigoid (MMP). Used topically, the drug may inhibit aldehyde deydrogenase (ALDH), which plays a key role in fibrosis, wrote JK Dart, UCL Institute of Ophthalmology, London.
Evidence weak for blue light-filtering IOLs
Only weak evidence supports the use of IOLs that filter visible blue light, researchers say. “On the basis of currently available evidence, one cannot advocate for the use of blue-light-filtering IOLs over UV-only filtering IOLs,” wroite X. Li, Waterford Institute of Technology, Waterford, Ireland, and colleagues.
Haze after PRK, LASIK tied to faulty epithelial regrowth
Poor regeneration of the epithelial basement accounts for most 'late haze' associated with PRK, LASIK, infections, or corneal transplants. Proper excimer laser maintenance may reduce irregularities.
Lifitegrast data support dry eye efficacy over placebo drops
Lifitegrast ophthalmic solution 0.05% (Xiidra, Shire) has demonstrated positive results for the treatment of the signs and symptoms of dry eye disease. Eye dryness scores for some patients have improved after two weeks of treatment with the topical drop.
No sign of chloramphenicol resistance in bacterial conjunctivitis
Chloramphenicol remains effective against Gram-positive bacteria, the most common agent in bacterial conjunctivitis, researchers say.
Autoantibodies may serve as glaucoma biomarkers
The loss of autoantibodies may serve as useful biomarkers for glaucoma, according to Nadine von Thun Und Hohenstein-Blaul, Johannes Gutenberg University Mainz, Mainz, Germany, and colleagues.
Clinicians coming to terms with dysfunctional lens syndrome
Using dysfunctional lens syndrome stages, physicians can discuss a range of treatment options with patients, based on clinical findings and refractive error.
Improving vision with electronic retinal implants
Electronic retina implants can restore enough vision for some patients to pursue tasks of daily living, according to RE MacLaren, part of a team testing the devices.
In vivo confocal microscopy ineffective for Fusarium and Aspergillus differentiation
It’s very hard to tell the difference between Fusarium and Aspergillus species with in vivo confocal microscopy (IVCM) of fungal keratitis, researchers say.
Protein fluorescence explored for cataract diagnosis
Protein fluorescence explored for cataract diagnosis
Fluorescence of lens proteins could help understand, diagnose, and treat cataracts, researchers say. “Rather than waiting for the condition to appear, it could be possible to diagnose and monitor cataract before it forms, allowing preventative measures to be taken where possible,” said Rory Duncan of Heriot-Watt University in Edinburh, United Kingdom in a press release.